USC ENDOCRINE LABORATORIES

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TEST INDEX


Thyroglobulin (Tg) Tg Antibody TSH Free T4 Total T4 Free T3 Total T3 TPO Antibody
THBR FT4I or FT3I TBG Calcitonin PTH


INTACT PARATHYROID HORMONE (PTH)

Methodology  Chemiluminescence Immunoassay

Performed  Mon - Fri

Reported  Mon – Fri

Collect  Serum:  One 6 mL RT (Min: 4 mL RT)     FNAW:  1.0 mL in saline

Transport  Serum:  2.0 mL frozen serum (Min: 0.5 mL)     FNAW: 1.0 mL frozen washout in saline

Stability  Stable for 2 months if frozen at -20°C.
           
Unacceptable  Slightly and moderately lipemic, hemolyzed or icteric samples are acceptable.  Samples that are grossly lipemic, icteric or hemolyzed are to be brought to the attention of the technical supervisor for approval.  Avoid using EDTA plasma.

Reference Range  Serum:  11-67 pg/mL      FNAW:  <10.0 pg/mL

CPT Code  83970

Information:  Parathyroid hormone (PTH) is secreted by four parathyroid glands that are located on the posterior surface of the thyroid gland and exerts significant influence in maintenance of optimal calcium ion concentrations.   PTH raises serum ionized calcium levels through direct action on bone and the kidneys:  PTH increases the rate of calcium ion flow from bone to the extracellular fluid, and increased both the renal tubular reabsorption of ionized calcium and renal excretion of phosphate.  Long-term regulation of total body calcium by PTH occurs through its stimulation of vitamin D synthesis in kidneys, which result in enhanced intestinal absorption of ionized calcium.  PTH is used in diagnosing primary and secondary hyperparathyroidism, hypoparathyroidism and to discriminate between hypercalcemia due to primary hyperthyroidism and hypercalcemia due to malignancy.

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