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Thyroglobulin (Tg) Tg Antibody TSH Free T4 Total T4 Free T3 Total T3 TPO Antibody
THBR FT4I or FT3I TBG Calcitonin PTH


Methodology  Radioimmunoassay
Performed  Mon – Fri

Reported  Next Working Day

Collect  One 6 mL RT (Min: 4 mL RT)

Transport  1.0 mL refrigerated serum (Min: 0.5 mL)

Stability  Stored at 2 - 8°C until used; Stable if frozen at - 20°C

Unacceptable: Whole blood/Plasma; Slightly and moderately lipemic, hemolyzed or icteric samples are acceptable.  Samples that are grossly lipemic, icteric or hemolyzed are to be brought to the attention of the technical supervisor for approval.

Reference Range  <0.4 U/mL

CPT Code  86800

Information: This highly sensitive, direct radioimmunoassay system is based on the use of a highly purified, stable preparation of 125I labeled Thyroglobulin.  The assay is standardized against the MRC Thyroglobulin Auto-antibody First International Reference Preparation (Coded 65/93).

Measurement of thyroglobulin auto-antibodies can be of considerable value in the diagnosis of thyroid diseases, such as autoimmune thyroiditis, Graves' disease, endemic goiter and subacute thyroiditis.  These measurements when used as part of a thyroid autoimmune diagnostic profile, which would include Anti Thyroid Peroxidase Antibody and Thyrotropin Receptor antibody, can be very useful in the differential diagnosis and management of thyroid disease.  TgAb is always to be run in conjunction with Thyroglobulin (Tg) sera in order to conform to NACB guidelines (Thyroid 13:1, 2003).

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