USC ENDOCRINE LABORATORIES

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TEST INDEX


Thyroglobulin (Tg) Tg Antibody TSH Free T4 Total T4 Free T3 Total T3 TPO Antibody
THBR FT4I or FT3I TBG Calcitonin PTH


ANTI-THYROID PEROXIDASE ANTIBODY (TPOAb)

Methodology  Radioimmunoassay

Performed  Tue & Thurs

Reported  Tue & Thurs

Collect  One 6 mL RT (Min: 4 mL RT)

Transport  2.0 mL refrigerated serum (Min: 0.5 mL)

Stability  Stored at 2 - 8°C until used; Stable if frozen at - 20°C

Unacceptable  Whole blood/Plasma; Slightly and moderately lipemic, hemolyzed or icteric samples are acceptable.  Samples that are grossly lipemic, icteric or hemolyzed
                                    are to be brought to the attention of the technical supervisor for approval.

Reference Range  <1.0 IU/mL

CPT Code  86376

Information:  Thyroid peroxidase autoantibodies (TPOAb) are of pathological importance because they are present in the majority of Hashimoto’s thyroiditis patients and correlate with the active phase of the disease.  Unlike thyroglobulin autoantibodies (TgAb), they may damage thyroid cells by complement fixation.  The detection of thyroid peroxidase autoantibodies (TPOAb) and thyroglobulin autoantibodies (TgAb), and the measurement of thyroid stimulating hormone, have been used in determining the diagnosis and management of autoimmune thyroid disorders.

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